Screening strategies include flexible sigmoidoscopy, that involves inserting a versatile optical device through the rectum into the lower part of the huge intestine, and colonoscopy, which involves inserting an extended flexible optical device through the rectum and in to the entire colon, is more expensive, has higher complication rates and usually is performed by a surgeon or gastroenterologist rather than a primary care physician. Anna L. Zisman, M.D., and co-workers at Evanston-Northwestern Healthcare, Feinberg School of Medicine, Northwestern University, Evanston, Ill., examined the records of 161,172 sufferers with colorectal cancer to assess whether certain risk factors, tobacco and alcohol use, should be considered in screening decisions also.‘Ficlatuzumab is the business lead antibody emerging from our promising antibody pipeline. Data from preclinical and Stage 1 research of ficlatuzumab demonstrate a well-tolerated profile and great combinability with EGFR inhibitors, such as gefitinib and erlotinib, and we look forward to continuing to advance ficlatuzumab in the clinic.’.. Acute kidney injury and chronic kidney disease are interconnected, say GW researchers For more than 40 years, physicians have treated diminished kidney function as two distinct syndromes: acute kidney injury and chronic kidney disease . However, latest epidemiologic and mechanistic studies suggest both syndromes are not unique entities, but interconnected.